Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β‐catenin modulator Annexin A1
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چکیده
منابع مشابه
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy.
Gut microbiota are linked to chronic inflammation and carcinogenesis. Chemotherapy failure is the major cause of recurrence and poor prognosis in colorectal cancer patients. Here, we investigated the contribution of gut microbiota to chemoresistance in patients with colorectal cancer. We found that Fusobacterium (F.) nucleatum was abundant in colorectal cancer tissues in patients with recurrenc...
متن کاملFusobacterium nucleatum and colorectal cancer: A review
Fusobacterium nucleatum (F. nucleatum) is a Gram-negative obligate anaerobe bacterium in the oral cavity and plays a role in several oral diseases, including periodontitis and gingivitis. Recently, several studies have reported that the level of F. nucleatum is significantly elevated in human colorectal adenomas and carcinomas compared to that in adjacent normal tissue. Several researchers have...
متن کاملFusobacterium nucleatum infection is prevalent in human colorectal carcinoma
Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma Mauro Castellarin, René L. Warren, J. Douglas Freeman, Lisa Dreolini, Martin Krzywinski, Jaclyn Strauss, Rebecca Barnes, Peter Watson, Emma Allen-Vercoe, Richard A. Moore, and Robert A. Holt BC Cancer Agency, Michael Smith Genome Sciences Centre, Vancouver, British Columbia V5Z 1L3, Canada; Department of Molecular Biol...
متن کاملFusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location
OBJECTIVES Evidence suggests a possible role of Fusobacterium nucleatum in colorectal carcinogenesis, especially in right-sided proximal colorectum. Considering a change in bowel contents and microbiome from proximal to distal colorectal segments, we hypothesized that the proportion of colorectal carcinoma enriched with F. nucleatum might gradually increase along the bowel subsites from rectum ...
متن کاملFusobacterium nucleatum empyema necessitans.
1. Allo MD, Miller J, Townsend T, Tan C. Primary cutaneous aspergillosis associated with Hickman intravenous catheters. N Engl J Med 1987;317: 1105–8. 2. Walmsley S, Devi S, King S, Schneider R, Richardson S, Ford-Jones L. Invasive Aspergillus infections in a pediatric hospital: a ten-year review. Pediatr Infect Dis J 1993;12:673–82. 3. Segal BH, DeCarlo ES, Kwon-Chung KJ, Malech HL, Gallin JI,...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2019
ISSN: 1469-221X,1469-3178
DOI: 10.15252/embr.201847638